šŸ”„šŸ”„ Donā€™t Miss Out on Our End of Autumn Sale. If you have any questions, feel free to click the bottom right corner to contact our customer service..

Concat us[email protected]
Shopping Cart

No products in the cart.

šŸ”
BS ISO 15819:2014

BS ISO 15819:2014

$102.76

Cosmetics. Analytical methods. Nitrosamines: Detection and determination of N-nitrosodiethanolamine (NDELA) in cosmetics by HPLC-MS-MS

Published By Publication Date Number of Pages
BSI 2014 22
PDF Format Searchable Printable Preview Now
Guaranteed Safe Checkout
Categories: ,

If you have any questions, feel free to reach out to our online customer service team by clicking on the bottom right corner. Weā€™re here to assist you 24/7.
Email:[email protected]

This International Standard describes a method for the detection and quantification of N-nitrosodiethanolamine (NDELA) in cosmetics and raw materials used in cosmetics.

This method is not applicable to the detection and/or quantification of nitrosamines other than NDELA nor to the detection and/or quantification of NDELA in products other than cosmetics or raw materials used in cosmetics.

If a product has a possibility of either NDELA contamination from ingredients or NDELA formation by the composition of ingredients, the method is intended to be applied for quantitative determination of NDELA. Accordingly, the method does not apply to routine testing of cosmetic products. Because of the large variety of cosmetic products within this field of application, this method might need to be adapted for certain matrices (refer to ISO 12787).

Therefore, International Standards dedicated to alternative methods for testing nitrosamines in cosmetic products are being developed separately. Other methods can be employed provided that they are verified as to their detection of NDELA and validated in terms of recovery and quantification of the analyte.

PDF Catalog

PDF Pages PDF Title
7 Foreword
8 Introduction
9 1 Scope
2 Normative references
3 Principle
10 4 Reagents
5 Apparatus
11 6 Sample preparation and conservation
6.1 General
6.2 Standard solutions preparation
12 6.3 Sample preparation
13 7 Procedure
7.1 General
7.2 Chromatographic conditions
14 7.3 HPLC-MS-MS conditions
15 8 Calculation of results
8.1 Determination of the R value
8.2 Calibration curve
8.3 Validity check procedure and its criteria
8.4 Calculation of concentrations
16 9 Test report
17 AnnexĀ A
(informative)

Examples of a calibration curve and of chromatograms

19 Bibliography

Related products

BS ISO 15819:2014
$102.76