{"id":386844,"date":"2024-10-20T03:37:20","date_gmt":"2024-10-20T03:37:20","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/bs-iso-134932021-tc\/"},"modified":"2024-10-26T06:37:09","modified_gmt":"2024-10-26T06:37:09","slug":"bs-iso-134932021-tc","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/bsi\/bs-iso-134932021-tc\/","title":{"rendered":"BS ISO 13493:2021 – TC"},"content":{"rendered":"
This document specifies the liquid chromatographic (LC) method for the determination of chloramphenicol content of muscle tissue of meat, including livestock and poultry.<\/p>\n
This document specifies the liquid chromatography tandem mass spectrometry method (LC-MS\/MS) for the determination of chloramphenicol content of muscle tissue, casing, liver of meat and meat products, including livestock and poultry.<\/p>\n
This document specifies LC-MS\/MS as the reference method.<\/p>\n
The LC method is suitable for the determination of chloramphenicol content greater than 6,5 mg\/kg.<\/p>\n
LC-MS\/MS is suitable for the determination of chloramphenicol content greater than 0,1 ?g\/kg.<\/p>\n
Test samples which have deteriorated cannot be analysed with this method.<\/p>\n
PDF Pages<\/th>\n | PDF Title<\/th>\n<\/tr>\n | ||||||
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1<\/td>\n | 30447121 <\/td>\n<\/tr>\n | ||||||
31<\/td>\n | A-30401653 <\/td>\n<\/tr>\n | ||||||
32<\/td>\n | National foreword <\/td>\n<\/tr>\n | ||||||
36<\/td>\n | Foreword <\/td>\n<\/tr>\n | ||||||
37<\/td>\n | 1 Scope 2 Normative references 3 Terms and definitions 4 Principle 4.1 Liquid chromatographic method <\/td>\n<\/tr>\n | ||||||
38<\/td>\n | 4.2 Liquid chromatography tandem mass spectrometry method 5 Sampling 6 Preparation of test sample 7 Test method of liquid chromatography 7.1 Reagents 7.1.2 Nitrogen, suitable for evaporating solvents. 7.1.6 Acetonitrile, HPLC grade. <\/td>\n<\/tr>\n | ||||||
39<\/td>\n | 7.2 Apparatus <\/td>\n<\/tr>\n | ||||||
40<\/td>\n | 7.3 Procedure 7.3.1 General 7.3.2 Test portion 7.3.3 Preparation of extract 7.3.4 Solid-phase extraction 7.3.5 Liquid-liquid extraction <\/td>\n<\/tr>\n | ||||||
41<\/td>\n | 7.3.6 Chromatographic analysis 7.4 Calculation <\/td>\n<\/tr>\n | ||||||
42<\/td>\n | 7.5 Precision 7.5.1 Interlaboratory test 7.5.2 Repeatability 7.5.3 Reproducibility <\/td>\n<\/tr>\n | ||||||
43<\/td>\n | 8 Test method of liquid chromatography tandem mass spectrometry method (reference method) 8.1 Reagents and materials 8.1.8 Methanol and water solution I (volume ratio 2:8). 8.1.9 Methanol and water solution II (volume ratio 1:1). <\/td>\n<\/tr>\n | ||||||
44<\/td>\n | 8.1.17 Acetonitrile and water solution (volume ratio 1:9). 8.2 Apparatus 8.2.1 LC-MS\/MS equipment. 8.3 Procedure 8.3.1 General 8.3.2 Test portion <\/td>\n<\/tr>\n | ||||||
45<\/td>\n | 8.3.3 Preparation of extract 8.3.4 Solid-phase extraction 8.3.5 LC-MS\/MS analysis <\/td>\n<\/tr>\n | ||||||
47<\/td>\n | 8.4 Calculation 8.5 Precision 8.5.1 Interlaboratory test 8.5.2 Repeatability <\/td>\n<\/tr>\n | ||||||
48<\/td>\n | 8.5.3 Reproducibility 9 Test report <\/td>\n<\/tr>\n | ||||||
49<\/td>\n | Annex A (informative) HPLC chromatogram of chloramphenicol standard solution and LC-MS\/MS chromatogram of chloramphenicol standard solution <\/td>\n<\/tr>\n | ||||||
52<\/td>\n | Bibliography <\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":" Tracked Changes. Meat and meat products. Determination of chloramphenicol content. Reference method<\/b><\/p>\n |